E-learning and e-modules, employed in medical education, have yielded positive learning outcomes across all learner groups and various educational contexts. In spite of the positive aspects of e-learning and e-modules, their full potential in medical education within India is still unrealized. The study's objective is to understand undergraduate student views on e-learning and e-modules using the Strengths, Opportunities, Aspirations, Results (SOAR) appreciative inquiry approach, and to identify the difficulties and obstacles.
This longitudinal study enrolled three subsequent groups of 250 first-year medical students and two subsequent groups of 100 first-year dental students. Using a purposive sampling method, the sample was selected. Based on the modified Zhou's Mixed Methods Model, two meticulously validated and structured questionnaires were developed for this study: the 'Knowledge, Attitude and Practice' (KAPQ) questionnaire for e-learning and the feedback questionnaire (FBQ) for e-modules. Prior to and subsequent to the introduction of e-modules, questionnaires were distributed through either MOODLE or hard copy. A tabulation of identified strengths, potential opportunities, probable aspirations, and likely results for e-learning and e-modules was generated from a qualitative analysis of student perceptions, sampled across three years from a large student body.
Six hundred and ninety students completed both questionnaires, yielding a response rate of 766%. Nine key themes were discovered within the Strengths domain, including: regular knowledge updates, innovative learning, constant accessibility, knowledge sharing, ample information, convenient access, knowledge as a source, creativity, and increased engagement. Eleven themes have been identified in the Opportunities domain. These encompass Clinical Skills training, Timesaving, Flexibility, Creativity, Increased engagement, Standardized content, Capacity building for students, Capacity building for faculty, Skills training, and Self-assessment. The Aspirations domain produced thirteen themes, the primary ones centering on: improving existing strengths, increasing future possibilities, and addressing the challenges and barriers as seen in the KAPQ and FBQ questionnaires. Four recurring themes in the analysis of barriers encompassed eye strain, distractions, a proclivity towards established methodologies, and internet connectivity challenges.
First-year medical and dental students at a private university located in Chennai, India, contributed the responses that shaped the findings of this qualitative investigation. To better engage students and support self-directed learning (SDL) in this population, implementing e-learning as blended learning, using structured and interactive e-modules, could be considered. Curriculum development, incorporating e-modules within blended learning strategies, may prove instrumental in the achievement of Competency-Based Medical Education (CBME) objectives in India.
This qualitative study's findings stem from the input of first-year medical and dental students attending a private university situated in Chennai, India. Using structured and interactive e-modules within a blended learning e-learning model, the learning experience for students in this population may be more engaging and encourage self-directed learning (SDL). Curriculum planning for blended learning, particularly when utilizing e-modules, may prove advantageous in fulfilling Competency-Based Medical Education (CBME) goals in India.

Postoperative adjuvant chemotherapy, a treatment for non-small cell lung cancer (NSCLC), demonstrably enhanced survival rates in the elderly population. medical crowdfunding We intended to evaluate the viability and efficacy of alternate-day S-1, an oral fluoropyrimidine, as adjuvant chemotherapy for the elderly with fully excised non-small cell lung cancer (NSCLC) of pathological stage IA (tumor diameter exceeding 2 cm) to IIIA (per the UICC TNM Classification of Malignant Tumours, 7th edition).
For one year, elderly patients were randomly categorized into two arms for adjuvant chemotherapy: Arm A, receiving oral S-1 (80 mg/m2/day) every other day, four days per week; and Arm B, receiving daily oral S-1 (80 mg/m2/day) for two weeks, followed by a seven-day rest period. As the primary endpoint, treatment completion rate, defined as the proportion of patients completing the six-month allocated intervention with a relative dose intensity (RDI) of 70% or more, assessed feasibility.
An enrollment of one hundred and one patients resulted in ninety-seven receiving the S-1 treatment protocol. At the six-month mark, the completion rate of treatment in Arm A reached 694%, while Arm B saw a completion rate of 646%. A statistically insignificant difference was observed (p = 0.067). Arm B's treatment completion rate exhibited a downward trend relative to Arm A's, particularly as the treatment duration extended to 9 and 12 months. A statistically significant difference (p = 0.0026 and p < 0.0001, respectively) was observed in the RDI of S-1 at 12 months and the completion of S-1 administration without dose reduction or postponement between Arm A and Arm B, with Arm A showing better outcomes. The frequency of anorexia, skin issues, and eye-related symptoms (lacrimation) was substantially greater in Arm B than in Arm A, according to statistical analyses (p = 0.00036, 0.0023, and 0.0031 respectively). A statistically significant difference (p = 0.022) was observed in the 5-year recurrence-free survival rates of Arm A (569%) and Arm B (657%). Arm A's 5-year overall survival rate was 686%, and Arm B's was 820% (p = 0.11).
The elderly patients with completely resected NSCLC showed successful tolerance to both daily and alternate-day oral S-1 administrations, exhibiting a lower frequency of adverse events, particularly in the Arm A group.
On April 25, 2012, the UMIN registry issued unique identifier UMIN000007819, with corresponding details accessible through this link: https://center6.umin.ac.jp/cgi-open-bin/ctr e/ctr view.cgi?recptno=R000009128. Trial jRCTs061180089, a clinical trial registered in Japan on March 22, 2019, and guided by the Clinical Trials Act, aims to focus on a particular clinical trial subject. The complete details can be accessed here: https://jrct.niph.go.jp/en-latest-detail/jRCTs061180089.
The registration of UMIN000007819, a unique identifier issued by UMIN, occurred on April 25, 2012, as indicated by the online resource at https://center6.umin.ac.jp/cgi-open-bin/ctr e/ctr view.cgi?recptno=R000009128. Registered in Japan on March 22, 2019, under the Clinical Trials Act, the jRCT trial, jRCTs061180089, is designed to move towards a specific clinical trial objective. Further details are provided at the specified link: https://jrct.niph.go.jp/en-latest-detail/jRCTs061180089.

Prior research fails to acknowledge the role of infrastructure in facilitating university technology transfer. China's high-speed rail, a significant contributor to its infrastructure, has exerted a major impact on its economy and society. whole-cell biocatalysis Applying a quasi-experimental design, using high-speed railway construction data and a comprehensive dataset of Chinese universities between 2007 and 2017, we analyze the effect of high-speed rail on university technology transfer activity. Extensive proof illustrates high-speed rail's positive influence on the transfer of university technology. The finding retains its validity, even after rigorous robustness tests were performed. Mechanism tests demonstrate that high-speed rail's influence on university technology transfer is undeniable, as it promotes engagement between universities and businesses and correspondingly increases businesses' demand for university technologies. Detailed examination shows that enhanced intellectual property safeguards increase the effect of high-speed rail on the technology transfer between universities, and this relationship between high-speed rail and university technology transfer is more notable in areas with less-developed trading systems for technology. Our investigation indicates that high-speed rail plays a significant role in influencing university technology transfer.

Beginning in 2014, Samgyeopsal has experienced a significant surge in popularity, becoming a widely appreciated cuisine in the Philippines. Carboplatin DNA Damage inhibitor The widespread availability of Samgyeopsal showcases its growing global appeal, extending its reach to countries including the United States, along with regions of Northern and Southern Asia. Using structural equation modeling and random forest classification, this investigation explored the propensity to eat Samgyeopsal during the COVID-19 pandemic. East Samgyeopsal consumption in the Philippines, exhibiting a high level of actual behavior, correlated strongly with utilitarian and hedonic motivations, Korean cultural influences, and consumer attitudes, as shown in the analysis of 1014 online responses. Subsequently, the impact of subjective norms, perceived behavioral control, and intention was demonstrably consequential, shaping the trajectory from intention to real-world actions. Last, the COVID-19 safety protocol displayed the least impactful data. In this study, the intention of Filipino consumers to eat Samgyeopsal during the COVID-19 pandemic is evaluated for the first time. This research's findings provide useful guidance for Korean BBQ restaurateurs and their global marketing endeavors. The model developed here can be applied to exploring consumer appetite for various food categories and international cuisines worldwide.

The infrequent occurrence of abdominal pregnancy, a particular type of ectopic pregnancy, has been reported at a frequency of about one in 10,000 live births. A high incidence of fetal and maternal morbidity and mortality is often observed in cases involving this. Acute hypotension, a symptom of a trauma activation, affected a 25-year-old primigravida female who experienced blunt trauma to the abdomen. This prompted the discovery of a viable abdominal pregnancy with placental separation. With hypotension and worrisome fetal heart tones evident, the medical team opted for an immediate exploratory laparotomy and emergency cesarean section in the operating room.